Abstract:Heroin overdose deaths have increased alarmingly in Chicago over the past decade. Naloxone, an opioid antagonist with no abuse potential, has been used to reverse opiate overdose in emergency medical settings for decades. We describe here a program to educate opiate users in the prevention of opiate overdose and its reversal with intramuscular naloxone.

Distinguishing signs of opioid overdose and indication for naloxone: An evaluation of six naloxone training and distribution programs in the United States by Traci C. Green, Robert Heimer, Lauretta E. Grau. This includes information on Chicago, New Mexico, San Francisco, Baltimore, and two sites in New York City